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IFN alpha-IFNAR-IN-1 hydrochloride
CAS No. 2070014-98-9
IFN alpha-IFNAR-IN-1 hydrochloride ( —— )
Catalog No. M26256 CAS No. 2070014-98-9
IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 53 | Get Quote |
|
| 5MG | 86 | Get Quote |
|
| 10MG | 116 | Get Quote |
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| 25MG | 201 | Get Quote |
|
| 50MG | 314 | Get Quote |
|
| 100MG | 470 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameIFN alpha-IFNAR-IN-1 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionIFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM.
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DescriptionIFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM.(In Vitro):IFN alpha-IFNAR-IN-1 hydrochloride inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 hydrochloride specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 hydrochloride exerts immunosuppressive activity by the direct interaction with IFN-α.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptorantimalarial
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Research Area——
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Indication——
Chemical Information
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CAS Number2070014-98-9
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Formula Weight315.9
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Molecular FormulaC18H18ClNS
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.CNCc1ccccc1Sc1cccc2ccccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Marcsisin SR, et al. Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds. Malar J. 2014 Jan 3;13:2.
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